Glaucoma Management

Cannabis has been shown to lower intraocular pressure (IOP) in individuals with glaucoma, a condition characterized by increased pressure within the eye that can lead to optic nerve damage and vision loss if left untreated.

One of the seminal studies on the potential of medicinal cannabis in treating glaucoma was conducted in the 1970s.

A landmark study by Dr. Robert Hepler and Dr. Thomas A. Petrus titled "Marihuana Smoking and Intraocular Pressure" was published in the Journal of the American Medical Association in 1971.

In this study, the researchers investigated the effects of smoking cannabis on intraocular pressure (IOP) in patients with glaucoma.

Here are some key findings from the study:

Reduction in Intraocular Pressure (IOP)

The study found that smoking cannabis led to a significant reduction in intraocular pressure in patients with glaucoma. The decrease in IOP occurred shortly after smoking and persisted for several hours.

Dose-Dependent Response

The researchers observed a dose-dependent response, with higher doses of cannabis resulting in greater reductions in intraocular pressure. However, they also noted that the duration of the pressure-lowering effect varied among individuals.

Sustained Use

The study indicated that the pressure-lowering effect of cannabis was most pronounced when the drug was used continuously throughout the day. Patients who smoked cannabis every 3-4 hours experienced sustained reductions in intraocular pressure.

Safety and Side Effects

While cannabis effectively lowered intraocular pressure, the researchers noted the psychoactive effects of the drug, including euphoria and altered perception.